Macrene Alexiades-Armenakas

Dr. Macrene Alexiades-Armenakas, a board-certified dermatologist with a clinical practice on Park Avenue in New York, is recognized worldwide as an authority on dermatology, laser surgery, and cutting-edge skincare ingredients. She holds BA, MD, and PhD degrees from Harvard and is an Associate Clinical Professor at Yale.

We’re huge fans of Macrene Alexiades-Armenakas, the New York-based dermatologist with a BA, MD, and PhD from Harvard. We’ve already interviewed Dr. A about her top anti-aging secrets, where she mentions why she developed her 37 Extreme Actives anti-aging cream. Read on for the inside scoop on recommendations she gives to the patients who include it in their skincare regimen.

AYLA: What type of skincare routine do you typically recommend for your patients using 37 Extreme Actives?
Dr. ALEXIADES-ARMENAKAS: My recommendation is to wash with lukewarm water in the morning and a gentle non-soap cleanser in the evening. While the skin is still damp, apply a spatula full of 37 Extreme Actives (usually a hazelnut size) to all 4 quadrants of the skin, around the eyes and mouth. Smooth in evenly. Do this, after cleansing, twice daily.

Any other products should go on top, since the 37 Extreme Actives absorbs directly into the skin due to the liposomes, and other products may interfere with the delivery of the actives.

As far as sunscreen is concerned, apply a mineral based sunblock 15 minutes prior to sun exposure and reapply every 2 hours, which is the typical length of time a sunblock works.

Finally, I do believe in chemical peels for skin rejuvenation and unclogging of pores, but only as often as once per month in the dermatologist's office. The skin has a 28-day turnover, so you don’t want to stress the new skin cells as they’re developing by re-peeling more often than that.

AYLA: Do you recommend anything in particular to your acne-prone patients?
Dr. ALEXIADES-ARMENAKAS: Avoid products with petrolatum or mineral oils, and avoid powders. These can clog pores and cause breakouts in susceptible individuals.

AYLA: All powders? Really?

Dr. ALEXIADES-ARMENAKAS: I hate to be the party pooper on powders, but this only pertains to people who suffer from breakouts. Some people are more predisposed to clogging than others. The ingredients that appear to be at play are mica and talc: the spicules get stuck on the pores and cause a backup of sebum behind them (the so-called "subterraneans," as my patients say — we call them closed comedones). I can undo the harm with chemical peels and an acne regime, plus 37 Actives, which does not block pores yet facilitates healing and skin turnover.

Want to simplify your skincare regimen with the uber-effective 37 Extreme Actives? Check out the formula for Balanced to Oily skin here and the Extra Rich formula for Balanced to Dry skin here.

About Dr. Alexiades-Armenakas: Macrene, who holds a BA, MD, and PhD from Harvard, is a Diplomate of both the American and European Boards of Dermatology and Associate Clinical Professor at Yale University School of Medicine. She runs a dermatology, laser surgery and research center in Manhattan and a lab-based skin care research company. Dr. Alexiades-Armenakas has numerous publications and discoveries in the fields of basic science, dermatology and laser surgery. Her practice and academic work are focused on topical dermatologic anti-cancer and anti-aging therapies, laser technology and skin rejuvenation. Learn more about Macrene’s impressive background here.

Any topic discussed in this article is not intended as medical advice. If you have a medical concern, please check with your doctor.