Macrene Alexiades-Armenakas

Dr. Macrene Alexiades-Armenakas, a board-certified dermatologist with a clinical practice on Park Avenue in New York, is recognized worldwide as an authority on dermatology, laser surgery, and cutting-edge skincare ingredients. She holds BA, MD, and PhD degrees from Harvard and is an Associate Clinical Professor at Yale.

We were delighted to host Dr. Macrene Alexiades-Armenakas, one of the most well-respected dermatologists in the country, for a conversation about all aspects of skincare. She shared so much useful information with us that we decided to capture it in a series of video interviews for you! In this video, she shares some key information about hyperpigmentation:

-Most common types – freckles, sun spots, and melasma
-How to effectively treat it at home
-Ingredients to look for, and ingredients to avoid

We hope you enjoy this rare opportunity to learn directly from Dr. Macrene — we adore this incredibly smart, kind, and accomplished skincare expert.

And when you're done watching, don't forget to check out our hyperpigmentation-fighting best sellers listed below.

  • 37 Extreme Actives and 37 Extreme Actives Extra Rich, non-comedogenic and oil-free anti-aging treatment moisturizers that tackle hyperpigmentation along with other signs of aging
  • Luzern Laboratories Serum Radiance, an Ayla customer favorite for hyperpigmentation treatment and a top choice during pregnancy
  • Medik8 CE-Tetra, one of our best sellers, is an excellent "starter" anti-aging serum that's great for skin all around — and vitamin C has long been a skincare industry standby for hyperpigmentation treatment

About Dr. Alexiades-Armenakas: Macrene, who holds a BA, MD, and PhD from Harvard, is a Diplomate of both the American and European Boards of Dermatology and Associate Clinical Professor at Yale University School of Medicine. She runs a dermatology, laser surgery and research center in Manhattan and a lab-based skin care research company. Dr. Alexiades-Armenakas has numerous publications and discoveries in the fields of basic science, dermatology and laser surgery. Her practice and academic work are focused on topical dermatologic anti-cancer and anti-aging therapies, laser technology and skin rejuvenation. Learn more about Macrene’s impressive background here.


Any topic discussed in this article is not intended as medical advice. If you have a medical concern, please check with your doctor.